PRX-T33 vs. BioRePeel: Which peel is right for you?

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Peelings are among the oldest methods for skin renewal. However, classic chemical peels often mean visible flaking and days of recovery. PRX-T33 and BioRePeel take a gentler approach: visible results without the typical peeling and without downtime. At alestetics in Zurich, we work with both – which one is right for you depends on your skin goals and type. Here you can read how they work and what differentiates them.

PRX-T33 – Biorevitalization without peeling

PRX-T33 is a non-ablative peel: it works deep down without removing the uppermost layer of skin. This is made possible by the combination of three active ingredients:

  • 33 % Trichloroacetic acid (TCA) stimulates fibroblasts to form new collagen
  • Hydrogen peroxide (H₂O₂) – buffers the acid on the surface so that no visible flaking occurs
  • Kojic acid – supports a more even skin tone

Unlike a classic TCA peel, PRX-T33 does not ablate the skin, but rather stimulates it from within. In a pilot study, this combination of TCA and hydrogen peroxide improved the appearance of sun- and age-related skin damage.Biron et al., 2022Read on to find out why collagen is the crucial building block and from when it declines Build collagen.

PRX-T33 is particularly suitable for declining skin elasticity and fine lines as with tired, Uneven complexion – on the face and neck, décolleté and hands. Because it works without open skin lesions, the risk of pigment shifts is low, which is also an advantage for sensitive and darker skin. The procedure takes around 30 minutes: cleansing, one to two massaged-in layers, washing off, aftercare – without redness or peeling. More on this on the treatment page. PRX-T33®.

BioRePeel – Exfoliation and skincare in two stages

BioRePeel is a biphasic peel: a lipophilic protective phase and a hydrophilic active ingredient phase. The protective phase coats the skin, strengthening the barrier and reducing irritation – which is why BioRePeel is also suitable for sensitive skin. The active ingredient phase combines:

  • 35 % TCA with fruit acids and salicylic acid (AHA/BHA/PHA) – for exfoliation and cell regeneration
  • Amino acids and vitamins – care for and support regeneration
  • GABA – for a smoothing effect

BioRePeel exfoliates and biostimulates in one step. It is particularly suitable for blemished, acne-prone skin, enlarged pores and a tired complexion. Mild peeling for one to two days is possible, but not the norm. More on this on the treatments page. BioRePeel®.

PRX-T33 vs. BioRePeel – the direct comparison

CharacteristicPRX-T33BioRePeel
TypeNon-exfoliating biorevitalizationBiphasic peel
FocusFirmness, elasticity, complexionExfoliation, pores, glow
Active ingredients33 % TCA + H₂O₂ + kojic acid35 % TCA + AHA/BHA/PHA + amino acids + GABA
Particularly withMature skin, losing elasticityblemished skin, pores, tired complexion
FlakingNonerare, mild (1–2 days)
Seasonall year roundall year round

We'll decide which is the best fit not based on trends, but on your skin goal – ideally based on the AURA 3D Skin Analysis.

Both as preparation for microneedling

PRX-T33 and BioRePeel can be combined well with other treatments. At alestetics, a simple rule applies: peeling comes before needling. A peel cleanses and exfoliates the skin, allowing the needles to penetrate more evenly. Studies show that the combination of chemical peeling and microneedling for acne scars yields better results than either method on its own.Review article, 2025. You can read about how it works here SkinPen® Microneedling.

Why PRX-T33 and BioRePeel at alestetics?

Both exfoliation treatments deliver visible results with no downtime – you can get straight back to your daily routine. Both can be carried out all year round, even in summer, and are suitable for most skin types. We’ll work with you to determine which one best supports your skincare goals – ideally based on a skin analysis.

Book your free AURA 3D skin analysis – no obligation, booked in two minutes.

What is the difference between PRX-T33 and BioRePeel?

PRX-T33 is a biorevitalization without peeling – it stimulates collagen in depth and stands for firmness, elasticity and a more even complexion. BioRePeel is a biphasic peel that exfoliates and nourishes – it is particularly suitable for impure skin, enlarged pores and tired complexions. Which one is right depends on your skin goal.

Does the skin peel after exfoliating?

With PRX-T33, usually not – it doesn't exfoliate the skin, but works underneath. With BioRePeel, slight peeling for one to two days is possible, but not the norm. Both treatments require no significant downtime.

Can I have PRX-T33 or BioRePeel done in the summer too?

Yes. Both are not photosensitising and therefore possible year-round, even in the warmer seasons. The risk of pigment displacement is low. Consistent sun protection afterwards remains important.

How many sessions will I need?

Both peels work best as a course of several sessions. Many achieve fresher skin even after the first treatment; the lasting improvement in texture and skin quality builds up over several appointments. We will determine the appropriate rhythm together.

Alexandra Stroganova – Founder of alestetics® Zurich

Written by

Alexandra Stroganova

Founder of alestetics® · Pre-ageing specialist

Medical beautician · V-NISSG-certified · Lymphatic therapist · since 2021

Alexandra founded alestetics® in Zurich in 2021. She works according to the ‘pre-ageing’ philosophy: improving skin quality early on, rather than trying to conceal it later.

Find out more about Alexandra and the team →
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