{"id":6745,"date":"2026-07-13T08:03:00","date_gmt":"2026-07-13T06:03:00","guid":{"rendered":"https:\/\/alestetics.ch\/?p=6745"},"modified":"2026-07-09T08:13:11","modified_gmt":"2026-07-09T06:13:11","slug":"polyphil-vs-polyphil-next","status":"publish","type":"post","link":"https:\/\/alestetics.ch\/en\/polyphil-vs-polyphil-next\/","title":{"rendered":"PolyPhil vs. PolyPhil Next: which variant for which skin?"},"content":{"rendered":"

In short:<\/strong> The difference is the hyaluronic acid. PolyPhil\u2122 contains pure polynucleotides (20 mg\/ml) and stands for regeneration and skin quality. PolyPhil\u2122 Next combines polynucleotides with hyaluronic acid (10 mg\/ml each) \u2013 for mature or dehydrated skin that needs extra moisture. There is also PolyPhil\u2122 Eye, specifically for the delicate eye area. Which variant is suitable depends on whether your skin primarily needs regeneration or regeneration plus moisture.<\/p>\n\n\n\n

When you choose PolyPhil\u2122<\/a> If you're interested, you'll quickly come across three names \u2013 and the question of which one is the right one. We'll explain the difference so that it sticks.<\/p>\n\n\n\n

All three are based on the same active ingredient<\/h2>\n\n\n\n

First, the commonality: all PolyPhil\u2122 variants are polynucleotide skin boosters from the Austrian brand Croma-Pharma, manufactured by Mastelli in Italy. The core is always the same \u2013 highly pure polynucleotides that stimulate the skin's own repair cells. None of these variants are fillers; none create artificial volume.<\/p>\n\n\n\n

The difference lies in what is additionally included and for which zone the formula is intended.<\/p>\n\n\n\n

PolyPhil\u2122 \u2014 the pure build-up formula<\/h2>\n\n\n\n

PolyPhil\u2122 contains 20 mg\/ml pure polynucleotides, without hyaluronic acid. This is the variant for skin quality and structure: it stimulates collagen and elastin, improves skin density and texture, and is well suited for thin, sun-damaged skin, as well as for support during Acne scars<\/a>.<\/p>\n\n\n\n

It's useful if your skin primarily needs renewal, and the moisture level is generally okay.<\/p>\n\n\n\n

PolyPhil\u2122 Next \u2014 Regeneration and Moisture<\/h2>\n\n\n\n

PolyPhil\u2122 Next combines 10 mg\/ml polynucleotides with 10 mg\/ml hyaluronic acid. The idea: biostimulation and immediate hydration in one step. The polynucleotides stimulate the cells, while the hyaluronic acid provides direct hydration.<\/p>\n\n\n\n

This variant is made for mature or dehydrated skin, which needs both simultaneously \u2013 building up from within and a moisture boost. Those who feel their skin appears dull and tired in texture often find this to be the right choice.<\/p>\n\n\n\n

PolyPhil\u2122 Eye \u2014 for the eye area<\/h2>\n\n\n\n

The skin around the eyes is thinner and more delicate than on the rest of the face. PolyPhil\u2122 Eye is specially formulated for this zone and works with adapted concentrations. The aim is firmness and hydration for tired, thin eye areas. More on this in the article Hyaluronic acid injections under the eyes<\/a>.<\/p>\n\n\n\n

The comparison at a glance<\/h2>\n\n\n\n
<\/th>PolyPhil\u2122<\/th>PolyPhil\u2122 Next<\/th>PolyPhil\u2122 Eye<\/th><\/tr><\/thead>
Active ingredient<\/strong><\/td>20 mg\/ml polynucleotides<\/td>10 mg\/ml PN + 10 mg\/ml HA<\/td>7.5 mg\/ml Polynucleotides<\/td><\/tr>
Focus<\/strong><\/td>Structure, skin quality<\/td>Regeneration + moisture<\/td>Eyelid skin firmness<\/td><\/tr>
Ideal for<\/strong><\/td>Thin, sun-damaged skin, acne scars<\/td>Mature, dehydrated skin<\/td>Tired, thin eye area<\/td><\/tr>
Volume<\/strong><\/td>No<\/td>No<\/td>No<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

How we choose the variety<\/h2>\n\n\n\n

In the alestetics\u00ae<\/a> At our clinic in Zurich, we don't determine the variant by trend, but by your skin's condition. We administer all three with the Vital Injector 2\u2122 \u2013 without welt or micro-papules. Often, only a close look at moisture, density, and zone will determine which formula is suitable.<\/p>\n\n\n\n

This view is provided by the free AURA 3D Skin Analysis<\/a>. Prices can be found on the PolyPhil\u2122 Page<\/a>.<\/p>\n\n\n\n

Read on<\/strong><\/p>\n\n\n\n